Endocrine Abstracts

Introduction: Increased exposure to sunlight and high serum levels of Vitamin D were reported to relate with decreased risk of various cancer types, such as prostate, breast and colon. Vitamin D receptor and 1α-hydroxylase expression were shown in papillary thyroid carcinoma. In this study, we aimed to evaluate serum 25-OH vitamin D levels in patients with benign and malignant thyroid nodulesMethods: Patients admitted to our thyroid clinic were recr...

Introduction: Type 1 diabetes mellitus (DM) is frequently associated with other autoimmune diseases. In this study, we aimed to evaluate thyroid autoantibodies, celiac antibodies and antiparietal antibody in patients with type 1 DM.Methods: Thyroid antithyroid peroxidase (anti-TPO) and antithyroglobulin (anti-Tg) antibodies, antiinsulin, antiislet cell and anti-glutamic acid decarboxylase (anti-GAD) antibodies, antiparietal antibody, antiendomisium, anti...

Introduction: Survival is increased in childhood-onset type 1 diabetes mellitus (DM) and approximately half of patients are diagnosed after the age of 15. Thus, a considerable number of patients with type 1 DM are adults. In this study, we aimed to investigate glycemic control and modalities of treatments in adult type 1 DM patients.Material and methods: Data of type 1 DM patients hospitalized between January 2004 and December 2009 were evaluated retrosp...

Introduction: Premature ovarian failure is cessation of ovarian function before the expected age, which is usually accepted to be 40. Autoimmune diseases are a frequently seen group of disorders causing premature ovarian failure. In this study, we aimed to evaluate the frequency of autoimmune thyroiditis in patients with premature ovarian failure.Material and method: Patients who admitted to our thyroid out patient clinic were included to our study. The ...

Introduction: Hypokalemic periodic paralysis associated with hyperthyroidism is a well-known acute electrolyte and acute muscle disorder. Lesser known is normokalemic periodic paralysis associated with hyperthyroidism (TNPP). Because plasma potassium is normal, and it can be misdiagnosed as some other disorder if thyroid function is not evaluated. We report a case of TNPP due to non-autoimmune thyroiditis.Case report: A 23-year-old woman was admitted to ...

Objective: We aimed to evaluate the frequency of malignancy in patients with follicular lesion or follicular neoplasia in cytological examination.Method: About 29 patients who had follicular neoplasia or follicular lesion in cytological examination after ultrasound guided thyroid fine needle aspiration biopsy (FNAB) were included in the study. Histopathologic results were evaluated after thyroidectomy in all patients.Results: There...

Objective: Role of thyroid stimulating hormone (TSH) in thyroid oncogenesis is not clear. There are few trials about relationship of TSH, thyroid hormones and autoantibodies with malignancy. We aimed to investigate thyroid function tests and malignancy in patients evaluated in thyroid disease council and decided to be managed with thyroidectomy.Method: About 272 patients were included in the study. Hyperthyroid and hypothyroid patients, patients on <smal...

Background: Gestational diabetes insipidus (DI) is a rare complication of pregnancy, usually developing in the last trimester and resolves spontaneously 4–6 weeks post-partum. It is mainly caused by excessive vasopressinase activity, an enzyme expressed by placental trophoblasts which metabolises arginine vasopressin (AVP). However in some cases, it can develop in a patient who had limited reserve of ADH and marginal central DI prior to pregnancy and may not reso...

Aim: Postoperative hypocalcemia is seen in 26-42% patients after parathyroidectomy.There are quite a lot of studies investigating preoperative factors that might be used to predict postoperative hypocalcemia in thyroidectomized patients, however there are less studies in parathyroidectomized patients.In this study, our aim was to determine whether any preoperative clinical, laboratory or ultrasonographical feature anticipate hypocalcemia in parathyroidectomized patients due to...

Background: Primary Hyperparathyroidism (PHPT) is a common endocrine disorder that is characterized by hypercalcaemia and elevated or inappropriately normal serum levels of parathyroid hormone. Most often, the presentation of PHPT is asymptomatic. PHPT can manifest with osteoporosis and hypercalciuria as well as with vertebral fractures and nephrolithiasis, both of which can be asymptomatic. Our aim in this study; to determine the frequency of kidney stones in patients operate...